abstract |
The present invention relates to the noval chemical compound of formula (I), it can suppress one or more kinases, especially suppresses SYK (spleen tyrosine kinase), LRRK2 (full asphalt mixture kinases 2) and/or MYLK (myosin light chain kinase) or its mutant.Described compound can be used for treating multiple disease.Described disease includes autoimmune disease, inflammatory diseases, osteopathia, metabolic disease, sacred disease and neurodegenerative disease, cancer, cardiovascular disease, allergy, asthma, Alzheimer, parkinson disease, skin disorder, oculopathy, infectious disease and hormone related condition. |