http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103487412-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d9de52bba13e16028dffa8775e3f3f28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-63 |
| filingDate | 2013-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc7e9f19af128fca21565dc51ea489a2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1ef2414e0db5867736f87a55636522a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d9b644c248c0b8e9e4307b1600d5353 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dce8b88aca1279ecac491aad81c3dddc |
| publicationDate | 2015-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103487412-B |
| titleOfInvention | Method for constructing rapid hepatotoxicity predication model of phenolic compound |
| abstract | The invention belongs to the technical field of rapid toxic substance detection, and particularly relates to a method for constructing a rapid hepatotoxicity predication model of a phenolic compound. According to the method, an HepG2/C3A cell with stable inheritance and high-expression cytochrome P450 is taken as a research object; 6 types of natural common phenolic compounds are selected and act on the cell respectively, and indexes such as cell CYPIA mitochondrial depolarization, ROS production rate and the like are tested respectively; and statistical analysis is combined, and finally, the prediction model is established. The method is simple and rapid and is used for predicating the hepatotoxicity of a drug, the result is stable, the accuracy is improved, and the method has a potential popularization and application prospect. |
| priorityDate | 2013-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 259.