http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103483310-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_08061393aa77382149d2ef8aca355508 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-16 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-16 |
| filingDate | 2013-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b672c3557c8b7e6e8791a8d84ab9bfc3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f028f2a5cdf2f15a1b90342880729b7 |
| publicationDate | 2015-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103483310-B |
| titleOfInvention | Synthesis method of 2-thiopheneethanol |
| abstract | The invention relates to a synthesis method of 2-thiopheneethanol, which comprises the following steps: adding thiophene and methylbenzene into a reaction vessel with mechanical stirring, adding sodium hydride in batches, heating to 40-50 DEG C, keeping the temperature for 4-6 hours, and introducing epoxyethane, wherein the mass volume ratio of thiophene, methylbenzene, sodium hydride and epoxyethane is 100g:(280-320)ml:(65-70)g:(66-70)g; and keeping the temperature for 10-14 hours, regulating the pH value of the reaction solution to 1-2 with dilute hydrochloric acid, regulating the pH value of the organic layer to 7-8 with a saturated sodium bicarbonate solution, washing the organic layer with a saturated saline solution, and concentrating the organic layer reduced pressure to a dry state to obtain the 2-thiopheneethanol. The according to the method, the sodium hydride used as a locating agent reacts with the epoxyethane to obtain the 2-thiopheneethanol by a one-pot process; and thus, the method has the advantages of short process route, cheap and accessible raw materials, high yield and good product quality, and is suitable for large-scale production. |
| priorityDate | 2013-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 37.