abstract |
The present invention relates to novel enhancers of protein production in host cells. It discloses a vector for expressing recombinant proteins in these cells, including encoding a) secreted peptide signal, b) 6-methylguanine-DNA-methyltransferase (MGMT, EC2.1.1.63) and Mutants or catalytic domains thereof, and c) the nucleotide sequence of the recombinant protein. The MGMT enzymes are preferably so-called SNAP proteins. |