abstract |
The invention discloses an 8-cyclohexyl-2-fluoro-vidarabine, a preparation method thereof and an application of 8-cyclohexyl-2-fluoro-vidarabine to treatment of leucocythemia. By using a synthesis method disclosed by the invention, a heavy metal catalyst in the current synthesis method is avoided, the synthesis operation is simplified, heavy metal residues in 8-cyclohexyl-2-fluoro-vidarabine are avoided, and the preparation method is suitable for research and further large-scale preparation of drugs. |