http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103467469-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-18 |
| filingDate | 2013-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103467469-B |
| titleOfInvention | A kind of separation method of triacetyl ganciclovir isomer |
| abstract | The invention discloses a kind of separation method of triacetyl ganciclovir isomer, described separation method comprises: (1) described triacetyl ganciclovir isomer crude product adds crystallization solvent, be warming up to backflow insulation, then be cooled to analysis of material, filter, washing, dry N7/N9 triacetyl ganciclovir isomer mixture; (2) N7/N9 triacetyl ganciclovir isomer mixture is added separation solvent orange 2 A, be warming up to the molten clear rear cooling of material and separate out solid, filter, be separated and obtain filtrate and filter cake, filter cake obtains N7 triacetyl ganciclovir isomer through washing, drying; (3) filtrate step (2) obtained and washings merging are evaporated to dry, and then add separation solvent B, and be warming up to reflux state insulation, solid is separated out in cooling, filtration, and filter cake obtains N9 triacetyl ganciclovir isomer through washing, drying.Separation method of the present invention is simple to operate, and separation efficiency is high, is separated the N9 enantiomeric purity obtained high. |
| priorityDate | 2013-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 65.