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filingDate 2013-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2015-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ca15132d2118bd741ff2594dc318612
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publicationDate 2015-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-103463189-B
titleOfInvention Method for extracting and separating total salvianolic acids from radix salviae miltiorrhizae water extract by utilizing ionic liquid
abstract The invention discloses a method for extracting and separating total salvianolic acids from a radix salviae miltiorrhizae water extract by utilizing ionic liquid. The method comprises the following steps: extracting the total salvianolic acids from the radix salviae miltiorrhizae water extract in an extraction mode by using imidazole hydrophobic ionic liquid as an extraction agent, and separating from tannin, polysaccharide, albumen and other impurities; performing back extraction on the extraction agent layer through high temperature or a basifier after the extraction is layered and separated to obtain a high-density total salvianolic acid aqueous solution or salt solution thereof which serves as a raw material for further refining, wherein the ionic liquid can be recycled as an extraction agent after the back extraction treatment. According to the method, the ionic liquid which is not volatile, inflammable or explosive is adopted to extract the total salvianolic acids, and total salvianolic acids enrichment and extraction agent regeneration can be realized by virtue of back extraction, so that the method has the advantages of simple and safe extraction process, and is easy for scale production, and an effective solution is provided to solve the production problem generated when inflammable and explosive organic solvents with strong volatilization are massively used in the process of extracting total salvianolic acids.
priorityDate 2013-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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