abstract |
A kind of Novel furanone derivative is provided, and comprises its medicine.This furanone derivatives is represented by formula (I), and wherein A represents-COOR1 or hydrogen atom; R1 represents hydrogen atom, the optional alkyl replaced, or the optional heterocycle replaced; R2 and R3 is identical or different and represents hydrogen atom independently of one another, the optional alkyl replaced, the optional phenyl replaced, the optional heterocycle replaced, the optional heterocycle condensed ring replaced, or the optional amino replaced; Or alternatively, R2 and R3, together with the nitrogen-atoms that they connect, can form the optional heterocycle replaced or the heterocycle condensed ring optionally replaced; And R4 represents hydrogen atom or halogen atom; Prerequisite is when A represents-COOR1, be the optional amino replaced, and when A represents hydrogen atom, R3 represents hydrogen atom when R2 with R3 is different. |