http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103450351-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_08dde60e3e0ca1e6ffaa5143e5c8477a |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-125 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14 |
| filingDate | 2012-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b0da1463b07685f05310be84994af8be |
| publicationDate | 2015-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103450351-B |
| titleOfInvention | Long-acting polypeptide for confronting Newcastle disease virus infection and modifier thereof |
| abstract | The invention discloses a polypeptide for confronting the Newcastle disease virus infection and a modifier thereof. The amino acid sequence of the polypeptide is the sequence 1 in the sequence table; the modifier is prepared by modifying the end of the amino group of the polypeptide with cholesterol, the modification is that the first amino acid in the sequence 1 in the sequence table is connected to the cholesterol. The polypeptide modifier provided by the invention can high-effectively prevent viruses from invading the host cells, has a prominent effect on inhibiting virus activity (the cellular level is 12 nM, the chick embryo level is 0.1 mg, and the chicken living body level is 0.5 mg), besides, only if the polypeptide or polypeptide modifier is intramuscularly injected in a time range of two days early to two day later of the Newcastle disease virus infection, the high pathogenicity virus infection which can invade into the hemato encephalic barrier of poultry can be effectively prohibited. The polypeptide for confronting the Newcastle disease virus infection and a modifier thereof provide an important basis for applications of polypeptide preparations and have an important application prospect and an innovative meaning in the field of animal medicine. |
| priorityDate | 2012-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.