http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103450195-B

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04
filingDate 2012-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2015-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c4e684638c813b97ad34d060415bc9a1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_310205baf5c2fc3564c67a26b238d27f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e81fda2445afb1a1f12a9f5f51c764e5
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01134b3cc920550655caf0d755a2e961
publicationDate 2015-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-103450195-B
titleOfInvention Tetrahydro-beta-carbolinyl-3-formic acid aliphatic chain alcohol esters, and preparation, nano structure, immunosuppression action and application thereof
abstract The invention relates to 6 aliphatic chain alcohol modified carbolinyl carboxylic acid analogs disclosed as general formula I, wherein n is equal to 6, 8, 10, 12, 14 or 16. The invention also relates to a preparation method of the 6 aliphatic chain alcohol modified carbolinyl carboxylic acid analogs disclosed as general formula I. The invention further relates to a nano structure of the 6 aliphatic chain alcohol modified carbolinyl carboxylic acid analogs disclosed as general formula I. By researching the inhibiting action of the saturated fatty chain alcohol modified carbolinyl carboxylic acid analogs on the spleen lymphocyte mitogen breeder reaction and the survival time after transplanting the mouse postotic cardiac muscle, the invention further relates to excellent immunosuppression action of the 6 aliphatic chain alcohol modified carbolinyl carboxylic acid analogs disclosed as general formula I. The 6 aliphatic chain alcohol modified carbolinyl carboxylic acid analogs with immunosuppressive activity disclosed as general formula I have wide application prospects in preparing immunosuppressive drugs.
priorityDate 2012-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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