http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103450195-B
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6b9ed41ec71e1e3d004841f54c9eabd8 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
filingDate | 2012-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2015-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c4e684638c813b97ad34d060415bc9a1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_310205baf5c2fc3564c67a26b238d27f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e81fda2445afb1a1f12a9f5f51c764e5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c97de6a01ed3841136b6755059e1090 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01134b3cc920550655caf0d755a2e961 |
publicationDate | 2015-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-103450195-B |
titleOfInvention | Tetrahydro-beta-carbolinyl-3-formic acid aliphatic chain alcohol esters, and preparation, nano structure, immunosuppression action and application thereof |
abstract | The invention relates to 6 aliphatic chain alcohol modified carbolinyl carboxylic acid analogs disclosed as general formula I, wherein n is equal to 6, 8, 10, 12, 14 or 16. The invention also relates to a preparation method of the 6 aliphatic chain alcohol modified carbolinyl carboxylic acid analogs disclosed as general formula I. The invention further relates to a nano structure of the 6 aliphatic chain alcohol modified carbolinyl carboxylic acid analogs disclosed as general formula I. By researching the inhibiting action of the saturated fatty chain alcohol modified carbolinyl carboxylic acid analogs on the spleen lymphocyte mitogen breeder reaction and the survival time after transplanting the mouse postotic cardiac muscle, the invention further relates to excellent immunosuppression action of the 6 aliphatic chain alcohol modified carbolinyl carboxylic acid analogs disclosed as general formula I. The 6 aliphatic chain alcohol modified carbolinyl carboxylic acid analogs with immunosuppressive activity disclosed as general formula I have wide application prospects in preparing immunosuppressive drugs. |
priorityDate | 2012-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 47.