http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103450128-B
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_07fef33cfcfb19e9e1eef6b9d09e677c |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-935 |
filingDate | 2013-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2015-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb0efed0d3bf3e4989785b24dbc51fa3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62aaee270a62af345a5bcd48f8153d6d |
publicationDate | 2015-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-103450128-B |
titleOfInvention | Preparation method of prostaglandin analogue midbody Corey aldehyde for treating glaucoma |
abstract | The invention discloses a preparation method of prostaglandin analogue midbody Corey aldehyde for treating glaucoma. The preparation method comprises the following steps: by taking Corey lactones and 2-iodoxybenzoic acid as basic raw materials, adding the raw materials and a solvent to a reaction container in sequence, heating for a reflux reaction, and after reaction, and cooling to a room temperature for filtration; and sequentially filtering and drying obtained filtrate, after drying, filtering, and removing the solvent from the filtrate by adopting conventional reduced pressure distillation, thus obtaining the product Corey aldehyde. The preparation method is used for preparing the midbody Corey aldehyde and has the characteristics that the operation is simple, the cost is relatively low, an adopted oxidizing agent is mild in property, stable in air, easy to store and the like; the whole operation process is relatively simple and convenient, and the purity and the yield of product are high. |
priorityDate | 2013-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 50.