http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103450128-B

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_07fef33cfcfb19e9e1eef6b9d09e677c
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-935
filingDate 2013-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2015-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb0efed0d3bf3e4989785b24dbc51fa3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62aaee270a62af345a5bcd48f8153d6d
publicationDate 2015-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-103450128-B
titleOfInvention Preparation method of prostaglandin analogue midbody Corey aldehyde for treating glaucoma
abstract The invention discloses a preparation method of prostaglandin analogue midbody Corey aldehyde for treating glaucoma. The preparation method comprises the following steps: by taking Corey lactones and 2-iodoxybenzoic acid as basic raw materials, adding the raw materials and a solvent to a reaction container in sequence, heating for a reflux reaction, and after reaction, and cooling to a room temperature for filtration; and sequentially filtering and drying obtained filtrate, after drying, filtering, and removing the solvent from the filtrate by adopting conventional reduced pressure distillation, thus obtaining the product Corey aldehyde. The preparation method is used for preparing the midbody Corey aldehyde and has the characteristics that the operation is simple, the cost is relatively low, an adopted oxidizing agent is mild in property, stable in air, easy to store and the like; the whole operation process is relatively simple and convenient, and the purity and the yield of product are high.
priorityDate 2013-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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