http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103435718-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 |
| filingDate | 2013-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103435718-B |
| titleOfInvention | The hyaluronic acid cholesteryl ester that PEG modifies |
| abstract | The present invention relates to hyaluronic acid cholesteryl ester and application thereof that a kind of new drug carrier PEG modifies.It introduces hydrophobic group cholesteryl ester and hydrophilic chain Polyethylene Glycol (PEG) on hyaluronic acid (HA) skeleton and is formed, have amphipathic, can be self-assembly of polymer micelle in water, bag carries insoluble drug, pharmaceutical grade protein, gene class medicine.The hyaluronic acid cholesteryl ester safety that this PEG modifies is good, biodegradable, critical micelle concentration is low；Carrier micelle nanoparticle is greatly improved dissolubility in the water of insoluble drug, and envelop rate is high；Preparation technology is simple, it is easy to large-scale production. |
| priorityDate | 2013-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 73.