http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103435509-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-10 |
| filingDate | 2013-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103435509-B |
| titleOfInvention | The preparation method of a kind of N-acyl acidic amino acid or its salt and application thereof |
| abstract | The invention discloses the preparation method of a kind of N-acyl acidic amino acid or its salt, comprise fat acyl chloride and amino acid carries out amidate action in the basic conditions, it is characterized in that, described amidate action take water as solvent, using acidic amino acid or its salt as main raw material, using a small amount of neutral amino acids or its salt as auxiliary material, under agitation, first fat acyl chloride is added drop-wise in the aqueous solution of acidic amino acid or its salt, adds the pH value that alkali regulates reaction solution; Deng fat acyl chloride be added drop-wise to a certain amount of after, add the aqueous solution of neutral amino acids or its salt, continue drip fat acyl chloride to being added dropwise to complete, stir maintain reaction.Described method adopts kilnitamin and fat acyl chloride to react under aqueous phase system, the transformation efficiency of amino acid and acyl chlorides can be significantly improved, remaining amount of amino acid significantly reduces, and product can directly use as tensio-active agent through simple process, and cost greatly reduces. |
| priorityDate | 2013-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 51.