http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103435440-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7972770ef102a9fbe63465770503126 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C25-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C17-363 |
| filingDate | 2013-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a54a44f5e43851d940d72993feed786 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90b94d46ffaa4b0c6e4e05f1295b7eea http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0550e913c10a0a3718dc99520c1bd326 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_425a2954fdd7967e6b54678cfd96a75c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_68781095f6240800fd5744f623efe374 |
| publicationDate | 2015-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103435440-B |
| titleOfInvention | Synthesis method of 1,2,4-trifluoro benzene |
| abstract | The invention discloses a synthesis method of 1,2,4-trifluoro benzene, and belongs to the technical field of chemical synthesis. The synthesis method is characterized by comprising the following reaction steps that (1) tetrachloro phthalic anhydride reacts with a methylamine aqueous solution, and 6-carboxyl-2,3,4,5-tetrachlorobenzene formyl methylamine is obtained; (2) 6-carboxyl-2,3,4,5-tetrachlorobenzene formyl methylamine reacts with zinc powder, and a mixture of 6-carboxyl-2,3,5-trichloro benzene formyl methylamine and 6-carboxyl-2,4,5-trichloro benzene formyl methylamine is obtained; (3) the mixture of 6-carboxyl-2,3,5-trichloro benzene formyl methylamine and 6-carboxyl-2,4,5-trichloro benzene formyl methylamine is subjected to backflow water diversion cyclization in sulfolane and toluene, and a mixture of 3,4,6-trichloro phthalic methylamine and sulfolane is obtained; (4) the mixture of 3,4,6-trichloro phthalic methylamine and sulfolane reacts with potassium fluoride, and 3,4,6-trifluoro phthalic methylamine is obtained; (5) 3,4,6-trifluoro phthalic acid is obtained by hydrolyzing 3,4-6-trifluoro phthalic methylamine; and (6) 1,2,4-trifluoro benzene is obtained by decarboxylizing 3,4,6-trifluoro phthalic acid. The synthesis method has the advantages that a raw material is easy to obtain; the method is easy and simple to operate; the purity of a product is good; and the method has a higher industrial application value. |
| priorityDate | 2013-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 68.