http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103418021-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_53b4d53983adbf56dd0e7d0bf96f8ce5 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D06M101-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D06M101-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L15-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D06M11-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D04H1-728 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D04H1-4382 |
| filingDate | 2013-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94acecba7bf17caa8ed2b1e5473220b5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a45a5e8dc11bf105f7caa3a309a6595e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5017c9224e448ae921f1c6eb736b7d41 |
| publicationDate | 2015-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103418021-B |
| titleOfInvention | In-situ-crossly-linked electrospun fibrous membrane dressing made from collangen I and preparation method of in-situ crosslinking electrospun fibrous membrane dressing |
| abstract | The invention discloses a preparation method of an in-situ-crossly-linked electrospun fibrous membrane dressing made from collangen I. According to the preparation method, the collagen I is dissolved in a novel environment-friendly solvent system (i.e. a composite system of [EMIM][Ac] and at least one lithium sal), so that the triple-helical structure of the collagen I is reserved to the maximum extent; natural cross-linking agent with good biocompatibility (alginate dialdehyde) is adopted to participate in the electrostatic spinning process of the collagen I, and crossly linked with the collagen I in situ. Secondly, through salt removal by simple water washing, freeze drying, sterilization and packaging, the in-situ-crossly-linked electrospun fibrous membrane dressing is obtained. The preparation method is simple and fast. Through the adoption of the preparation method, industrial production can be realized easily, and potential biotoxicity risks, brought by glutaraldehyde crosslinking agent, which is adopted universally at present, are effectively avoided. The in-situ-crossly-linked electrospun fibrous membrane dressing prepared according to the preparation method has the advantages of high biocompatibility, no cytotoxicity and high biological activity. |
| priorityDate | 2013-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 52.