http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103417568-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7004 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-14 |
| filingDate | 2013-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103417568-B |
| titleOfInvention | The preparation method of Mannitol sodium chloride injection |
| abstract | Mannitol sodium chloride injection provided by the invention and preparation method thereof, belongs to field of pharmaceutical technology.Mainly solve the problem that when 5 hydroxymethyl furfural measures in prior art, trap exceeds standard.Be characterized in: the every 1000ml consumption of prescription, supplementary material is: glycerol 99 ~ 101g, fructose 49 ~ 51g, sodium chloride 8 ~ 10g, fresh water for injection adds to 1000ml.Preparation method is: account for the sodium chloride, glycerol, the fructose that add recipe quantity in the dense preparing tank of the water for injection of the cumulative volume 30% that makes up a prescription successively to access, after raw material all dissolves, opens dense preparing tank liquid outlet, dilute preparing tank inlet, squeezes into dilute preparing tank; Amass to 99% with water for injection complement, adjust ph is between 3.8 ~ 4.2; Entering fill after inline final filter through being equipped with 0.22 μm of polyether sulfone filter element filters, obtaining described injection; Product does not add stabilizing agent and the trap of 5 hydroxymethyl furfural is less than 0.6. |
| priorityDate | 2013-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.