http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103405408-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-352 |
| filingDate | 2013-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103405408-B |
| titleOfInvention | The application of chrysin in treatment ischemic cerebral apoplexy Chinese medicine |
| abstract | The invention discloses the application of chrysin (Chrysin) in treatment ischemic cerebral apoplexy Chinese medicine.Experimental result of the present invention shows that chrysin focal cerebral ischemia-reperfusion injury has good neuroprotective, the neurological deficit after cerebral ischemia reperfusion injury can be improved, alleviate brain water content, reduce cerebral infarction volume, increase superoxide dismutase (SOD) vigor, reduce malonaldehyde (MDA) content; After Focal Cerebral Ischemia Reperfusion, chrysin can reduce the relative expression quantity of the nuclear Factor-Kappa B (NF-κ B) of reperfusion brain, nitric oxide synthase type (iNOS), COX-2 (COX-2) gene; Chrysin also can reduce the expression of GFAP, Iba1 in reperfusion brain; suppress astrocyte and microglial activation; reduce the expression of the Pro-inflammatory Cytokine such as IL-1 α, IL-1 β, IL-6, IL-12, IL-17A, TNF-α, IFN-γ simultaneously; thus alleviate the excessive inflammatory response of ischemic tissue of brain, realize the neuroprotective after ischemia. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109061139-A |
| priorityDate | 2013-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 248.