http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103394076-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_057e3f7e1b8d0b6bd0e933a5bc1883ba |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-765 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-08 |
| filingDate | 2013-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_220f8870ef6bed3d38cfef05c6e5e513 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a6e88e161310ea2dbaf4c24d90d83d4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a7748c417105fc0393d1189c479d2128 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a69ad8a007ca7aee4edb3c7d61a10d36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a84d2b07b482774e5fa19fe57dac9110 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0e824865461ea2a5d949ca441139fb9 |
| publicationDate | 2015-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103394076-B |
| titleOfInvention | Process for preparing human serum albumin |
| abstract | The invention discloses a process for preparing human serum albumin. According to the process, a low-temperature ethanol separation method is adopted, and the human serum albumin is prepared from human plasma. The process comprises the steps of dissolving plasma; preparing an ingredient I; preparing an ingredient II and an ingredient III; preparing an ingredient IV; preparing an ingredient V; refining the ingredient V; carrying out ultrafiltration; diluting; carrying out pasteurization; sterilizing and packaging albumen; incubating products; and packaging finished products. The process has the advantages that solid-liquid separation is carried out by adopting a pressure filtration technology, so that the albumin yield which is higher than 29 g/L plasma is increased remarkably, the purity is higher than 98%, and the stability of the products is improved remarkably; Zetaplus deep filter-core filtration is combined with the prolongation of pasteurization time, so that the PKA (Protein Kinase A) level of the products is effectively controlled to be lower than 20IU/ml, and the risks of excessive heat source and virus infection in the products are reduced; and during the process, sodium chloride solutions of two gradient concentrations are used for carrying out ultrafiltration, so that not only can the ethanol residual quantity of the products be controlled to be lower than 0.025%, but also the aluminum residual quantity can be effectively minimized to be lower than 50 micrograms/L. |
| priorityDate | 2013-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 46.