abstract |
The invention provides a kind of diaminopyrimidine derivatives or its pharmacy acceptable salt, its preparation method, containing its medical composition and its use.Described diaminopyrimidine derivatives or its pharmacy acceptable salt function are as 5-HTn 4 receptor stimulant, thus can be used for prevention or treatment gastrointestinal peristalsis dysfunction, the one of gastrointestinal tract disease, as gastroesophageal reflux disease (GERD), constipation, irritable bowel syndrome (IBS), maldigestion, postoperative intestinal obstruction, delayed gastric emptying, gastroparesis, intestinal pseudo obstruction, drug-induced transport delay or diabetic gastroatonia. |