http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103381143-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7c0a5a3e19633705b74da621161347d5 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-56 |
filingDate | 2012-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_626a91a76612498fceb11c77acb06af7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cdedb357c25a314eb6c0065fcfadb124 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d19b0b642de3f19b124502188b6ec5c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a7005de42df5068aaed119186515746 |
publicationDate | 2013-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-103381143-A |
titleOfInvention | Polymer-coated oleanolic acid liposome and preparation method thereof |
abstract | The invention belongs to the technical field of medicine and relates to a polymer-coated oleanolic acid liposome and a preparation method thereof. The preparation method comprises the following steps of preparing an oleanolic acid liposome suspension, adding a polymer into the oleanolic acid liposome suspension, carrying out coating to obtain a polymer-coated oleanolic acid liposome suspension, and carrying out spray drying or freeze drying to obtain polymer-coated oleanolic acid liposome powder, wherein before use, hydration reconstruction is carried out according to requirements. The polymer-coated oleanolic acid liposome utilizes long-circulating characteristics, biological adhesion and penetration promotion of the coating material, improves drug encapsulation efficiency and liposome stability, prolongs in-vivo residence and cycle time of particulates, promotes intercellular transmembrane transport of the particulates, improves oral bioavailability of oleanolic acid, is processed into solid powder, and is convenient for package, storage, transport and use. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104983684-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104984339-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104984339-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104814928-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104814928-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104983684-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104622808-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112999197-A |
priorityDate | 2012-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 80.