abstract |
On the one hand, the present invention relates to the compound with following formula (I):n wherein Rn 1 to Rn 6 , a, b, Z and X as in specification sheets define, or its pharmaceutically acceptable salt.These compounds have enkephalinase inhibit activities.On the other hand, the present invention relates to the medical composition comprising described compound; Use the method for described compound; With for the preparation of the method for described compound and intermediate. |