| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_279b4c171d4ef5996ccd96c093a55ddf |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-84 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-81
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-06 |
| filingDate |
2013-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2014-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2fd70a8732ae3c3c32c78b2d6a443380
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5cf59f215847082ca7fb863ed2b260a4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_52718f00176272cf1df82a18fcd0b0ac
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_163a245654bc096044076a5021835d7e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d8679a58700bde1348d746ed1dc37db
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_433968e3d7bd4a76d9071c87946c5e69 |
| publicationDate |
2014-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-103374557-B |
| titleOfInvention |
Mannose glycosylated lysozyme and application thereof |
| abstract |
The invention relates to a mannose glycosylated lysozyme and an application thereof. The lysozyme is subjected to n-glycosylation and is particularly glycosylated by mannose on the site N-X-S/T, wherein X is an amino acid except proline. The invention further provides a method for preparing the mannose glycosylated lysozyme. According to the method, the n-glycosylation site is added manually and the pichia pastoris mannose is used for expressing an obtained product so that the natural lysozyme which is not subjected to glycosylation is constructed and further subjected to the n-glycosylation. The mannose glycosylated lysozyme provided by the invention has the bacterium killing activity, can enter the cell under the mediation and the endocytosis of a mannose receptor on the macrophage membrane to kill the intracellular bacteria and has a potential medicinal value. |
| priorityDate |
2012-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |