http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103374548-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6d107a89d33f1e93a1563a81d5e5b6ab |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0783 |
| filingDate | 2012-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e18f65cc5deae6000eb815cc3d1fd916 |
| publicationDate | 2013-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103374548-A |
| titleOfInvention | High-efficiency amplification culture solution for tumor infiltration lymphocytes |
| abstract | The invention provides a high-efficiency amplification culture solution for tumor infiltration lymphocytes. The culture solution contains IL-2, IL-12, anti-CD28 and anti-CTLA-4. Compared with the prior art, the high-efficiency amplification culture solution has the advantages that a combined serum-free culture medium containing IL-2, IL-12, anti-CD28, anti-CTLA-4 and other cell factors is adopted, the amplification efficiency of TIL cells is obviously improved, and the amplification efficiency is about 3-10 times higher than the amplification efficiency of a common amplification culture solution; moreover, an inhibitory function of Treg lymphocytes on cytotoxic T lymphocytes can be effectively achieved, and the amplified lymphocyte has an extremely strong tumor killing effect. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106085956-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108707580-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106399239-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108753717-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103823068-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108753718-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103823068-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021239083-A1 |
| priorityDate | 2012-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 76.