http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103374020-B
Outgoing Links
Predicate | Object |
---|---|
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D513-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate | 2012-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-103374020-B |
titleOfInvention | The naphthalene-ring containing thiazole of one class [4,5-b] quinoxaline derivatives and method for making thereof |
abstract | The present invention relates to the naphthalene-ring containing thiazole [4 of a class, 5-<i>b</iGreatT. GreaT.GT] and quinoxaline derivatives and preparation method thereof, the thiazole that derivative of the present invention is special quinoxaline skeleton structure have the advantage of thiazole and quinoxaline two kinds of heterocycles concurrently simultaneously, conformation is more stable, has manyly to form site compared with strong interaction with acceptor molecule; And the auxiliary group naphthalene nucleus introduced on this basis and pyrazoline are all commonly in medicine intermediate have antibacterial and structure that is anti-tumor activity, increase the ratio of active group, each provide lipophilic end and water-wet side, for molecule transmission in vivo and permeable membrane provide larger may. |
priorityDate | 2012-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 83.