http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103351420-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J75-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J71-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 |
filingDate | 2013-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-103351420-B |
titleOfInvention | Detached compound and its preparation method and application from Fructus Momordicae charantiae |
abstract | The invention belongs to pharmaceutical technology field, disclose one group of detached noval chemical compound 5 from Fructus Momordicae charantiae α ,19S‑epoxy‑19,23‑dimethoxycucurbita‑6,24‑dien‑3 β ‑ol,5 α ,19R‑epoxy ‑19,23‑dimethoxycucurbita‑6,24‑dien‑3 β ‑ol,5 β , 19R epoxy 19,23 dimeth oxycucurbita 6,24 dien 3 β ol, and5 β, 19S epoxy 19,23 dimethoxycucur bita 6,24 dien 3 β ol and its preparation method and application, the Fructus Momordicae charantiae being dried is passed through alcohol extraction, concentrates, obtain I, II, III and IV crude product through hydrolysis and silica gel column chromatography again, K4 is obtained final product, K4 is prepared through efficient liquid-phase chromatography method, obtains new compounds i, II, III and IV after recrystallization.I, II, III and the IV of present invention preparation has preferable hypoglycemic activity. |
priorityDate | 2013-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 167.