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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01L3-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N1-28
filingDate 2013-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2015-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e12d51ac8d6bb75019033cfc5f8e61d8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_708825c535289c820d1f87e5e3285989
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publicationDate 2015-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-103344464-B
titleOfInvention Micro-fluidic agglutinin chip for glycosyl separation, and preparation method thereof
abstract The invention relates to a micro-fluidic agglutinin chip, specifically to a method for preparing and modificating a micro-fluidic chip. The micro-fluidic chip is designed and prepared through a micro electro mechanical technology. Dissolved bacterial cellulose is regenerated in a micro channel to be as a filling material of chip channel columns, and agglutinin is fixed on the filling material surface which is subjected to hydrophilic modification; and according to specific affinity effect of agglutinin to glycosyl, substances containing specific glycosyl on the surface, such as glycoprotein and lipopolysaccharide and the like, are separated. The chip consists of a glass base material, channel graph is etched on the base material by an ultraviolet etching technology, and high-temperature bonding is performed by program temperature control. The chip is provided with an inlet and an outlet of a separation sampling, an inlet and an outlet of the filling material, a bacterial cellulose filled column, a sample micro channel and on-line monitoring points. By taking regenerated bacterial cellulose as the chip filling material, the micro-fluidic agglutinin chip has the main advantages of being excellent in effects of bacterial cellulose, simple in fixing step of agglutinin, convenient to perform spectrum monitor, and substantial in glycosyl separation effect.
priorityDate 2013-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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