http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103340823-B
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f312cc7676e939dee48fb4fdfe921ce8 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-20 |
filingDate | 2013-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2015-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c47b7b7b5956e2fc9f6ca4230e7f8aa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c06ce8df28b9abac7cd6853aa44b8e65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed19f7488bddb1bf2cc139ede0a55f01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b0014de8b2c77585f2b285aab7eef1ee http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8fcfcac393b9a71e42b1abca3cc4f74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9629ae28aa0735a082bad168ab828a8d |
publicationDate | 2015-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-103340823-B |
titleOfInvention | Formulation of paeonol proniosomes and preparing method thereof |
abstract | The invention discloses a formulation of paeonol proniosomes and a preparing method thereof. The preparing method comprises the steps: firstly, dissolving 3 to 6 parts of paeonol, 64 to 145 parts of a non-ionic surfactant, 64 to 145 parts of lecithin and 7 to 13 parts of cholesterol into 1 to 3 parts of an organic phase, capping and sealing, and heating in a water bath to dissolve all the ingredients completely; and then adding 1-3 parts of an aqueous solution, heating in the water bath again to form a clear solution, and cooling to the room temperature to obtain the paeonol proniosomes. The paeonol proniosomes are in a semi-solid gel state, can be recombined to form non-ionic surfactant niosomes after hydration, provide a effective method for solving the problems of easy aggregation and easy fusion of niosomes and leakage of drugs in a solution state and a storage process of the non-ionic surfactant noisomes, have obvious superiorities in transportation, storage and use, are suitable for industrial production, and are used as quite promising novel carriers. The paeonol proniosomes can be directly applied to skins, and also can be prepared into a gel agent, an ointment, a patch and other transdermal drug delivery formulations. |
priorityDate | 2013-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 83.