http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103319608-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_09732f873ca8bfa73eae25f3dade1df1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6f609b11d6b89e691a4f07436c7113ab |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-866 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23K1-16 |
| filingDate | 2013-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_619f1395a8425e147c667765dd23edd0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd3f1f1ebe0e73bf67934d9f8ff57eb7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45cd069173d1094cfffd30eaba7089e8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17331359c300a55bdf03f972c84236de http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58b26232ceb4890021eaf6685cf6d2bf |
| publicationDate | 2014-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103319608-B |
| titleOfInvention | Pig IFNalpha1-Fc fusion protein as well as encoding gene and expression method thereof |
| abstract | The invention provides a pig IFNalpha1-Fc encoding gene optimized according to a silkworm reaction system, a fusion protein expressed by the pig IFNalpha1-Fc encoding gene and a method for expressing pig IFNalpha1-Fc fusion protein by utilizing a silkworm bioreactor and belongs to the field of biologic gene engineering. As a non-specific broad spectrum antiviral biological agent, a pig interferon alpha 1 has a wide medical prospect, and but being similar to most gene engineering veterinary medicines, the pig interferon alpha 1 has the problems of underproduction, expensive price, irregular quality and short action time. According to the Pig IFNalpha1-Fc fusion protein, a silkworm expression system is used for expressing an optimized pig IFNalpha1-Fc fusion gene to obtain a target protein with relatively high expression efficiency and relatively strong activity. Besides, according to the pig IFNalpha1-Fc fusion protein provided by the invention, the action time of the pig interferon alpha 1 is prolonged, the integral immune adjustment effect is enhanced, and the later-period purification is facilitated, so that the mass production of pig IFNalpha1-Fc fusion protein preparations is realized by utilizing a gene engineering method, and conditions for developing novel feeds containing the fusion proteins are created. |
| priorityDate | 2013-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 61.