http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103319376-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C277-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C279-14 |
| filingDate | 2013-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103319376-B |
| titleOfInvention | The preparation method of creatine hydrochloride |
| abstract | <b> the present invention relates to a kind of preparation method of creatine hydrochloride, and it comprises the following steps of carrying out successively: (</b><bGreatT.Gre aT.GT1</b><bGrea tT.GreaT.GT), in dehydrated alcohol, add anhydrous creatine while stirring; (</b><bGreatT.Gre aT.GT2</b><bGrea tT.GreaT.GT), control temperature is </b><bGreatT.Gre aT.GT10</b><bGre less than atT.GreaT.GT DEG C, the ethanol solution of containing hydrogen chloride is added in the feed liquid that step (</b><bGreatT.Gre aT.GT1</b><bGrea tT.GreaT.GT) obtains, creatine hydrochloride is generated after stirring, wherein, described anhydrous creatine and the mol ratio of described hydrogenchloride are </b><bGreatT.Gre aT.GT1:1.01 ~ 1.02</b><bGreatT .GreaT.GT, (</b><bGreatT.Gre aT.GT3</b><bGrea tT.GreaT.GT), the creatine hydrochloride generated is separated after drying, obtain creatine hydrochloride.Preparation process of the present invention is simple, and the cycle is short, does not use acyl chloride chemical, thus there is not its degradation production.Do not need heating in reaction, do not need distillation and concentration, without the need for machine solvent wash, thus environmental friendliness, target product purity is high, yield is high, cost is low.</b> |
| priorityDate | 2013-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.