abstract |
Immunostimulant can be adsorbed in insoluble metallic salt such as aluminium salt, to change its pharmacokinetics, pharmacodynamics, intramuscular retention time and/or immunostimulating effect.Modify immunostimulant to introduce certain part if regulating the acid salt group of seeing of absorption.These modified compounds are even at keeping or improve its vivo immunization activity when delivering with adsorption form. |