| abstract |
The invention provides dopa oxidase activity inhibitor, Melanin inhibitor, skin-whitening agents or skin preparations for extenal use using peristrophe or its extractive with organic solvent or the represented compound of following formula (I) or its salt as active ingredient (in formula (I), R 1 And R 2 Represent the alkoxyl that hydroxyl or carbon number are 1～4, or R 1 And R 2 Form together methylene-dioxy; R 3 And R 4 Represent the alkoxyl that hydroxyl or carbon number are 1～4, or R 3 And R 4 Form together methylene-dioxy; R 5 Represent hydrogen atom, hydroxyl, the alkoxyl that carbon number is 1～5, the saccharide residue such as acyl group or (D-β-D-furans celery glycosyl) oxygen base that carbon number is 1～4; R 6 And R 7 For hydrogen atom and R 8 And R 9 Represent together oxygen atom, or R 8 And R 9 For hydrogen atom and R 6 And R 7 Represent together oxygen atom. ) |