http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103304733-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F220-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F220-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F220-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F271-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F226-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F222-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F2-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32 |
| filingDate | 2013-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103304733-B |
| titleOfInvention | A kind of preparation method and application of degradable environment-responsive polymer nano hydrogel |
| abstract | The invention belongs to technical field of polymer materials, the preparation of a kind of degradable environment-responsive polymer nano hydrogel and application.The present invention is with N caprolactam as principal monomer, with N, N ' double (acryloyl) cystamine is cross-linking agent, and to introduce the hydrophilic monomers such as methacrylic acid, n-methylolacrylamide, polyethylene glycol monomethyl ethermethacrylic acid esters (Mw=2000) be comonomer, obtained the polymer nano hydrogel of degradable multiple environment-responsive by precipitation polymerization preparation method.Raw material of the present invention is easy to get, and preparation method is simple, with water as solvent, and environmental sound.The polymer nano hydrogel good dispersion prepared, size is homogeneous, has good stability and biocompatibility.By controlling consumption and the pH value of environment of methacrylic acid, N n-methylolacrylamide, polyethylene glycol monomethyl ethermethacrylic acid esters etc., the phase transition temperature of scalable polymer, thus can be applicable to the fixed point release of medicine, as the carrier of drug targeting release. |
| priorityDate | 2013-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 47.