http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103304566-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-18 |
| filingDate | 2013-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103304566-B |
| titleOfInvention | A kind of crystallization type Entecavir |
| abstract | The present invention relates to the preparation method of a kind of new crystallization type Entecavir and this crystallization type Entecavir, the X-ray powder diffraction figure of described new crystallization type Entecavir is in 2 θ=16.435 ° (d=5.38925), 2 θ=19.704 ° (d=4.50199), there is stronger diffraction peak at ° (d=3.50703) place, 2 θ=25.376, on differential thermal analysis collection of illustrative plates, start to occur a dehydration endotherm melting peak at 79.1 DEG C, an endothermic melting peak is there is at 140.1 DEG C, at the endothermic melting peak that about 244.6 DEG C appearance one are sharp-pointed, during to about 299.2 DEG C, sample starts to dissolve.Crystallization type Entecavir of the present invention when comparatively preparation is made in Entecavir hydrate crystallization, has better dissolution rate, and crystal formation has relatively better stability. |
| priorityDate | 2013-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.