http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103304446-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9083f8824b83211e2a0503686f35ca06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C269-02 |
| filingDate | 2013-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5cffd1d7dc0ecb3bae3bd611cc0ed3a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5bbb34dfba12b33526131850e07e260d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cee58f50c52ce4f666fcd2ede1714635 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7ec7ded39de07fd701dab3caa8f4f6d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5dc9a1ad97990de35ebb64708681f93f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17f7f0f23e3f61b3d8c415ea9c474d77 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51e4a4df32efca0632bcbd871e288f55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a97faf3426749b2d46b4540cdd0822f2 |
| publicationDate | 2015-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103304446-B |
| titleOfInvention | Derivatization method of optically active phenylacetylene compound |
| abstract | The invention provides a derivatization method of an optically active phenylacetylene compound. The derivatization method comprises the following steps of: (1) carrying out an amidation reaction between 4-ethynylbenzoic acid and a chiral amino alcohol to synthesize an optically active phenylacetylene derivative with an active hydroxyl; and (2) further carrying out a derivatization reaction between the optically active phenylacetylene derivative with the active hydroxyl and isocyanate so as to synthesize an optically active phenylacetylene derivative with a carbamate group. The derivatization method provided by the invention has the characteristics of simple process operations, moderate reactions and less by-products. Besides, the phenylacetylene derivative obtained by the derivatization method provided by the invention has high stability and good optical activity, and has potential application value in the fields such as asymmetric synthetic catalyst, chiral resolution, chiral reagent, medicine, pesticide and the like. |
| priorityDate | 2013-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 116.