http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103304440-B

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filingDate 2012-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2015-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36e5bdcf450e07146dffbb8d84dfe65a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_32c88f8b712efe7a41dd177540698600
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publicationDate 2015-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-103304440-B
titleOfInvention 3-[2-(aryl propylenine)hydrazino]-ethyl benzoate compound and application thereof
abstract The invention relates to a 3-[2-(aryl propylenine)hydrazino]-ethyl benzoate compound and an application thereof. The 3-[2-(aryl propylenine)hydrazino]-ethyl benzoate compound is a compound as shown in the formula I or a pharmaceutically acceptable salt (refer to the claim 1 for the specific structure). The compound provided by the invention has strong inhibitory activity on the close related protein-protein interaction in a human immunodeficiency virus gene integration process, namely the human immunodeficiency virus (HIV)-1 integrase and lens epithelium derived growth factor (LEDGF)/p75 interaction. The result proves that the compound provided by the invention is hopefully developed to be a novel target anti-acquired immune deficiency syndrome pharmaceutical for the protein-protein interaction.
priorityDate 2012-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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