http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103301120-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_303dbfb519abd95c01389cc4c9838e6f |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4172 |
| filingDate | 2013-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ef3a3574bf845944a15010e37fa9a98 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de5e1f6d9fd04b9284cb3ee7e34ce1fa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0978ae00ebb41d3e1a2dfa7c9ceb0a3c |
| publicationDate | 2014-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103301120-B |
| titleOfInvention | Preparation method of compound amino acid injection |
| abstract | The invention provides a preparation method of a compound amino acid injection. The preparation method is characterized by comprising the following steps of: weighing 18 amino acids, sodium hydrogen sulfite and sorbitol according to the weighs specified in the formula of the compound amino acid injection per 1000 ml; adding water for injection to a pot, preserving heat at a temperature ranging from 65 to 75 DEG C, feeding NaOH to the water so that the NaOH is dissolved into 0.1 M NaOH; feeding L-cystine, blasting nitrogen into the pot, stirring for dissolving, adding water to 50% of volume, and then feeding sodium hydrogen sulfite, the left amino acids of the 18 amino acids and sorbitol, and stirring until all the materials are completely dissolved; performing activated carbon adsorption, suction filtration and refined filtration, keeping the constant volume after cooling; continuously introducing nitrogen in the dissolving process, and charging nitrogen until the quantity of residual oxygen is lower than 3% before filling; and finally, carrying out filling and sterilization. The preparation method of the compound amino acid injection is characterized in that the preparation process is simplified, the preparation time is shortened, the dosage of a pH regulator is quantized rationally and the quality risk can be reduced. Besides, the preparation method is low in requirements for the conditions of the production equipment and easy for the production workers to operate. |
| priorityDate | 2013-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 67.