http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103288822-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_32622955710a511ff5d89f584662fe2f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_92367512a7327e197920165b674c7aac |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D461-00 |
| filingDate | 2013-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_edd15261f766360c84da1e7335308bcd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_892afbef56884f0d36e759102582f904 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9add802eb8cae4239483c701447c987a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a272ccf03435736a8a168bf888ee399 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dfc5e945103af1bd1ca3aa9dbd89502c |
| publicationDate | 2015-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103288822-B |
| titleOfInvention | Preparation method of vinpocetine |
| abstract | The invention relates to a preparation method of vinpocetine. The preparation method comprises the following steps of: (1) in the presence of mixed acid, reacting apovincaminic acid with absolute ethyl alcohol in a heating condition to obtain a reaction solution; (2) condensing the reaction solution at reduced pressure, diluting the concentration residue using water, adjusting the pH (Potential of Hydrogen) to 8-9, carrying out extraction by using an organic phase, washing the organic phase by using a saturated saline solution, dewatering and drying the organic phase, and carrying out filtration, reduced-pressure concentration and recrystallization, and drying to obtain the vinpocetine. The preparation method provided by the invention has the characteristics of environment protection and the like and is simple and convenient to operate, and the prepared vinpocetine has the advantages of high purity, controllable impurity, low cost and the like. |
| priorityDate | 2013-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 75.