abstract |
The present invention relates to compound of formula I and pharmaceutically acceptable salt, ester and prodrug, they are syk inhibitors of kinases.The invention still further relates to the intermediate for preparing this compound, prepare various disease conditions, the method for such as non Hodgkin lymphom that the method for these compounds, the Pharmaceutical composition containing these compounds, the method for suppression syk kinase activity, the method for suppression platelet aggregation, and prevention or treatment are at least partly mediated by syk kinase activity. |