http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103275152-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-08 |
| filingDate | 2013-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103275152-B |
| titleOfInvention | A kind of preparation method of high-purity fidaxomicin |
| abstract | The invention discloses the method for separation and purification feldamycin from feldamycin fermentation mycelium.The method is first by feldamycin filtering fermentation liquor, lixiviate, is decoloured, adsorbs, resolves after vat liquor dilute with water by macroporous resin, and gained desorbed solution obtains feldamycin crude product after concentrated, extraction, drying; Then dissolved by feldamycin crude product polar organic solvent, injection of polymer microballoon post carries out chromatographic separation, obtains highly purified fidaxomicin.The inventive method effectively eliminates the interference of fermentation secondary metabolite, improves quality and the product yield of feldamycin.Whole technique is simple, easy to operate; Prepared fidaxomicin can for medicine; Prepared feldamycin purity is greater than 95.0%, and omnidistance total recovery is greater than 45%.Solvent for use is Conventional solvents, and toxicity is little, is suitable for suitability for industrialized production. |
| priorityDate | 2013-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.