http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103275151-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-08 |
| filingDate | 2013-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103275151-B |
| titleOfInvention | A kind of process for purification of Matachrom |
| abstract | The invention provides a kind of process for purification of Matachrom.A process for purification for Matachrom, mainly comprises (1) and carries out preliminary decolouring impurity elimination to erythromycin diafiltration liquid flocculation agent, extract after being purified liquid with erythromycin special solvent, further to decolour impurity elimination to extraction liquid gac.(2) by process after erythromycin extraction liquid phase inversion to purifying aqueous phase, again the erythromycin in aqueous phase is extracted in N-BUTYL ACETATE, cyclohexane mixed solvent, utilize the method for two-step crystallization to obtain erythromycin crystal liquid, be dried after separation to Matachrom finished product.In finished product, Erythromycin A content reaches more than 83%.The present invention is directed to traditional processing technology utilizes special solvent to extract erythromycin from erythromycin diafiltration liquid, then the crystallization of extraction liquid is carried out, finally be dried after separation to the shortcoming that in Matachrom finished product, Erythromycin A content is low, decolouring impurity elimination is carried out to diafiltration liquid and extraction liquid, the method of two-step crystallization after phase inversion, improves the content of Erythromycin A in Matachrom finished product. |
| priorityDate | 2013-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 38.