http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103275072-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-14 |
| filingDate | 2013-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103275072-B |
| titleOfInvention | The preparation method of saracatinib |
| abstract | Present invention is disclosed a kind of preparation method of saracatinib, it comprises the steps: 7-[2-(4-methyl isophthalic acid-piperazinyl) oxyethyl group]-5-[(tetrahydrochysene-2H-pyrans-4-base) oxygen base]-3,4-dihydroquinazoline-4-ketone (II) and 6-chloro-2,3-methylenedioxyphenyl amine (III), under organic bases and condensing agent effect, carries out a step condensation reaction and obtains saracatinib (I).Compared with prior art, this preparation method's raw material is easy to get, concise in technology, mild condition, environment optimization and Quality advance, adapts to suitability for industrialized production, promotes the development of the economic technology of this bulk drug. |
| priorityDate | 2013-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 77.