http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103275012-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_089d40759d5e23b2760341e8f5fd5ce8 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-58 |
| filingDate | 2013-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c72b1255851d7d9f19d942460a9a9db0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_504a7e4dd30e4a5a48c5e33e19fb57ce http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_caa28439149fab5987550774d97068a0 |
| publicationDate | 2015-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103275012-B |
| titleOfInvention | Preparation method and application of Maca alkaloid |
| abstract | The invention discloses a preparation method and an application of Maca alkaloid. The method comprises the steps in sequence as follows: (1), Maca is smashed, a certain volume of an acid alcohol solution is added, supersonic extraction is performed for 1-3 times, the mixture is filtered, and an extracting solution is combined and concentrated, so that extractum is obtained; (2), the extractum is dissolved with acid water and filtered, the pH value is adjusted to be 9-12, the mixture is leached with chloroform or ethyl acetate, and an extraction liquid is subjected to pressure reduction concentration and dried, so that a Maca alkaloid crude extract is obtained; and (3), the Maca alkaloid crude extract is subjected to column chromatography with high-speed countercurrent and alkaline alumina, an eluent comprising a target compound is combined, and a solvent is recycled, so that a Maca alkaloid compound is obtained. According to the method, the technological operation is simple, the preparation amount is large, the sample loss is small, the separation effect is good, the energy consumption is low, the pollution is small the method is suitable for large-scale preparation, and a Maca alkaloid monomer obtained through separation is high in purity, has a better antineoplastic activity, is suitable for preparing antineoplastic drugs and neoplasm prevention health-care food, and has a better application and development prospect. |
| priorityDate | 2013-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 72.