http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103271889-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-18 |
filingDate | 2013-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2015-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2015-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-103271889-B |
titleOfInvention | Novel paliperidone progressively-increarelease release osmotic pump preparation and preparation method thereof |
abstract | The present invention belongs to technical field of medicine, discloses a kind of 9-hydroxy-risperidone bilayer and increases progressively osmotic pump controlled release tablet and preparation method thereof.This osmotic pump preparation is by medicated layer, boosting layer composition label and the semi-transparent coating membrane composition be wrapped in drug release hole outside label, intermediate molecular weight polyoxyethylene (mean molecule quantity 900 is employed in medicated layer, 000 ~ 1,000,000) and a certain proportion of osmo active substance, make medicine layer hydration rate moderate, utilize double-deck label single coats that the release of active medicine can be made substantially to present and increase progressively releasing trend, and can maintain and increase progressively release 14 ~ 24h.Said preparation significantly can reduce adverse effect, improves the compliance of patient, and said preparation preparation is simultaneously simple, significantly simplifies the preparation technology increasing progressively osmotic pump preparation, is more conducive to suitability for industrialized production. |
priorityDate | 2013-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 74.