http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103269761-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-3274 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-3219 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-3212 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-3809 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-286 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-289 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-745 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K17-00 |
filingDate | 2011-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-103269761-B |
titleOfInvention | affinity chromatography matrix |
abstract | The present invention relates to separate the method for protein that one or more contain immunoglobulin (Ig) from liquid. First described method comprises makes liquid and contains the isolation medium that is fixed on the part on holder and contact; By making the protein adsorption that contains immunoglobulin (Ig) on matrix with ligand interaction; Then clean the optional step of adsorbing the matrix that has the protein that contains immunoglobulin (Ig) on it; And by making matrix and the protein that discharges the eluent of protein and contain immunoglobulin (Ig) described in contacting to reclaim. Described method is the improvement of previous separation method, each part comprises one or more albumin A domains (E, D, A, B, C) or albumen Z or its functional variant, does at least one monomer have at the B domain corresponding to albumin A or albumen Z? the replacement of the locational asparagine of N28, and wherein said part provides the increase of wash-out pH compared with unsubstituted part. |
priorityDate | 2010-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 57.