http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103266133-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-93 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 |
| filingDate | 2013-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103266133-B |
| titleOfInvention | The construction method of stably express clinic lamivudine drug resistance hepatitis B virus cell strain |
| abstract | The invention discloses the construction method of the cell strain of stably express lamivudine drug resistance hepatitis B virus, make HBV full genome be incorporated in Polymerase chain reaction HepG2 cellular genome by cell biological molecular techniques, produce the autonomous of virus and replicate and complete life cycle events.Cell strain constructed by the present invention can support the high level duplication of HBV DNA and the stably express of antigen, and lamivudine has height drug resistance, it is adaptable to the in-vitro screening research of HBV biological characteristics, resistance mechanism and novel antiviral medicine. |
| priorityDate | 2013-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 104.