http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103265551-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_483f92b202be1d8fdef023310c92360d |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-22 |
| filingDate | 2013-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8538ef03d608088411210dc0817cb956 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_923f067434f0786f582f7a4795589e86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ab51db4ef3a39866d27fea3677a4afa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_088db5650ba56cfc26d2f17945d95a02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2670e7f81aed8a662a4824bbbf66a4ee |
| publicationDate | 2013-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103265551-A |
| titleOfInvention | Method for synthesizing camptothecin serving as active intermediate of anti-tumor medicament |
| abstract | The invention discloses a novel synthetic method for camptothecin serving as an intermediate of anti-tumor medicament irinotecan hydrochloride and various functional medicament camptothecin derivatives. According to the technical scheme, the method mainly comprises the following steps of: (1) obtaining a compound 2 from a compound 1; (2) obtaining a compound 3 from the compound 2; (3) obtaining a compound 4 from the compound 3; (4) obtaining a compound 6 from a compound 5; (5) obtaining a compound 7 from the compound 6; (6) obtaining a compound 8 from the compound 7; (7) obtaining a compound 9 from the compound 8; (8) obtaining a compound 10 from the compounds 4 and 9; and (9) obtaining a compound 11 from the compound 10, namely (20S)-camptothecin. By adopting the technical scheme, the method can be used for efficiently completing full synthesis of the camptothecin with short route based on simple commercial raw materials by using common reagents and simple operation. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110092752-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110092752-B |
| priorityDate | 2013-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 48.