http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103265545-B
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_217f2be73fd6be0be36dd55803d3bec5 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
filingDate | 2013-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2015-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3b2e86ccb99c449e71d512d5cf82acd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d62088877114309370e2e103fbc9600 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b840caa337ce7a953506f15a165f276 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e423d8535d25892a4d11217d6db1950 |
publicationDate | 2015-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-103265545-B |
titleOfInvention | Method for preparing parazole iso-indole compound |
abstract | The invention relates to a method for preparing a parazole iso-indole compound. According to the technical scheme, the method comprises the following steps of: preparing an ortho-alkynyl benzaldehyde derivative through Sonogashira reaction by taking an ortho-bromobenzene formaldehyde derivative and an acetenyl compound as the raw materials; and further taking the ortho-alkynyl benzaldehyde derivative as the raw material, adding methanol as the solvent, subsequently adding a ketone compound, hydrochloric acid hydrazine and alkali, uniformly stirring, and further preparing the parazole iso-indole compound under temperature raising and backflow condition in one step. The method has easily-accessible raw materials, is short in synthesis route, simple to react and operate, rapid in reaction speed, easy in aftertreatment, high in yield and small in environmental pollution, has objective economic practical values and at the same time has wide application prospects in the field of medicine synthesis. |
priorityDate | 2013-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 53.