| abstract |
The present invention relates to 2-amino-4-arylthiazole derivatives as TRPA (transient receptor potential subfamily A) modulators. In particular, the compounds described herein are useful in the treatment or prevention of diseases, conditions and/or disorders modulated by TRPA1 (transient receptor potential subfamily A, member 1). Also provided herein are methods for preparing the compounds described herein, intermediates used in their synthesis, pharmaceutical compositions thereof, and methods for treating or preventing diseases, conditions and/or disorders regulated by TRPAl. |