http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103254151-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D275-06 |
| filingDate | 2012-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103254151-B |
| titleOfInvention | Benzo isothiazole 5-LOX and mPGES-1 inhibitor and application |
| abstract | The invention discloses a kind of benzo isothiazole compound of the difunctional inhibitor as 5-lipoxygenase (5-LOX) and Prostaglandin E Synthase (mPGES-1), there is structure shown in formula IV, wherein: Rn 1 , Rn 2 , Rn 3 represent hydrogen, alkyl, alkoxy or halogen separately, or Rn 2 with Rn 1 or Rn 3 cheng Huan, Joint Representative's 1,3-butadiene subunit.This compounds to be lived test to the enzyme of the external of 5-LOX and mPGES-1 and whole blood, confirms that the difunctional inhibitor of its 5-lipoxygenase and Prostaglandin E Synthase is active, can be used for the medicine prepared treatment and prevent various inflammation. |
| priorityDate | 2012-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 94.