http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103254109-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_615bd7f2c0a8cad77f76b71d1fb9f42a |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-335 |
| filingDate | 2013-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2be091337eee294e91b052b312f7b585 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d963cb96c92a27cdff4257a9b4e17f7 |
| publicationDate | 2015-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103254109-B |
| titleOfInvention | Benzoyl pyrrole derivative and synthetic method thereof |
| abstract | The invention relates to a benzoyl pyrrole derivative as a medicament intermediate and a synthetic method thereof. The synthetic method comprises the steps of synthesizing 2-isopropyl aminomethyl pyrrole by taking pyrrole as a raw material through a mannich reaction, and then synthesizing a target compound by taking aromatic aldehyde as an acylation reagent. According to the benzoyl pyrrole derivative and the synthetic method thereof, the use of non-environment-friendly chlorinated reagents such as benzoyl chloride and phosphorus oxychloride with larger toxicity can be avoided, and the problems of large potential safety hazard, serious pollution of three wastes and the like in a traditional technique can be thoroughly solved. The method is economical and environment-friendly, mild in reaction conditions, simple for product separation, abundant in raw material resources, and easy for industrialized production. |
| priorityDate | 2013-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 57.